Human Cloning

"Science without conscience is the death of the soul." Rabelais 1537

What Exactly Is Cloning?  

In order to understand cloning a basic understanding of human and animal reproduction will be helpful, but if Biology wasn't your best subject in school, don't worry - we will take you through this gently. Let's start with a basic definition of the term.   Cloning is the process of creating an organism or being that is genetically identical to its parent. Note the singular use of the word "parent".  This is because most clones are a result of a process called asexual reproduction, whereby the new organism develops from only one parent, rather than two.  In this literature, we will be discussing two types of cloning:  Twinning and somatic cell transfer.

How is Cloning Done?

The first method, twinning, is a procedure that was used to create twin monkeys at the Primate Research Center in Oregon.  In this method the female egg was fertilized by a male monkey outside the womb, thereby using two parents in the creation of an embryo.   As soon as any egg is fertilized by the sperm it begins dividing - from two cells to four to eight, etc. The fertilized egg is then allowed to grow and divide until it reaches the eight-cell stage. At this point, once those eight cells are then separated, from the original embryo,  they  can be implanted  into the uterus of eight separate surrogate mothers, producing eight clones.  And when these cells are separated from the original embryo, that embryo is destroyed in the process - the same procedure used with Embryonic Stem Cell Research

You Mean Cloning Is Used In Embryonic Stem Cell Research? 

Cloning is a major part of Embryonic Stem Cell (ESC) research, which involves the deliberate destruction of the embryo in order to obtain the stem cells.  In order to push for federal funding, scientists say they only intend to use existing "left-over" embryos from IVF (in-vitro fertilization) clinics. And the reason is simple: they intend to use cloning to produce an unlimited supply.  However, it doesn't stop there.  Adult stem cells are also used in cloning.

How Are Adult Stem Cells Used?

In a method known as "somatic cell transfer", whereby the somatic, or adult stem cells provide the nucleus - the chromosomal DNA material for a newly developing embryo.  This is pretty much the process that was used to clone Dolly the sheep.

How was Dolly the Sheep Created?

The production of Dolly involved two cells: a donor cell (in this case, an adult sheep cell) and a recipient, unfertilized egg cell.  Using these two cells: 

1) The nucleus of the recipient egg cell was removed, eliminating its genetic information

2) The donor cell, taken from the udder of an adult which contained the DNA and genetic information was "fused"  with the egg cell

3) An electric pulse was used to "jump-start" the development of the egg into an embryo

4) The embryo was implanted in the uterus of the surrogate mother sheep and carried to term.  The donor or recipient ewes in this experiment actually could have been the same sheep used to carry Dolly to term, had it not been that the animals were too old.

What Was This Clone Like?

The newborn sheep had all the same characteristics of any other "normal" sheep, and carried the exact genetic makeup of the donor.  However it is unknown whether there may be hidden characteristics or adverse effects that might surface after a number of years.  For example, cloning experiments on other animals have shown a marked increase in the size of the offspring (they are larger) and there is also a tendency for short survival spans and massive genetic abnormalities.

So With The Dolly Method, No Embryo Was Destroyed?

Unfortunately, that is not the case.  There were 276 failed attempts to create one sheep. Aside from all the miscarriages and stillborns, defective embryos were also destroyed. Some may marvel at the end result, but there was nothing admirable in the life obliterated in the process.  

What Are Other Problems with Cloning?

Scientists have had a success rate in cloning of less than 3% at best and the results are often grotesquely deformed creatures. Further, the genetic reprogramming that is done can subtly alter genes with consequences that are not readily apparent but will surface later on. These clones appear "normal" on the outside, but they are later found to have a host of problems, including developmental delays, lung problems, heart defects, neurological disorders and malfunctioning immune systems. 

This Sounds A Little Scary…

It should!  Just because we are technically able to do something, doesn't necessarily mean we should do it. Unfortunately in a self-centered society, we are led to believe we should be able to have whatever we want.  Science, however, should be treated somewhat like the forbidden fruit in the Garden of Eden. Some things, no matter how tempting, some things should not be touched.

Besides Destroying & Creating Life, What Other Problems Are There?

To name a few…

Creation of Humans for Research

By substituting a human in the "twinning" method of cloning from the previous page, when the eight cells are split off to become eight new embryos, you now have eight new human lives and eight times as many laboratory specimens.  Scientists would have an endless supply of human guinea pigs - a fact already noted by some scientists at the National Institutes of Health.  In their zeal for federal funding of ESC Research, they revealed their callous disregard for human life by stating that  the use of these embryos would "reduce the need for laboratory animals in research"….putting the value of human life lower than that of a laboratory rat!

Therapeutic Research

Using somatic cell, or nuclear transfer, we would create a new life - just like Dolly.  But instead of implanting this life into a uterus, scientists allow the embryo to develop to just the right stage - then extract the stem cells, which of course destroys the embryo, and voila!  You now have your very own set of embryonic stem cells to create spare parts for yourself.   But human life was created and destroyed - a clone of one's own flesh and blood - in order to obtain them.  And you thought only animals consumed their young!

Genetic Manipulation:

Much has been in the news about "tailor made, custom-ordered" babies, using traits of gifted or “desirable”  people who donate their eggs or DNA  to produce the perfect child. Hitler had the very same idea.  By using the same process as Dolly the sheep, we could fuse a human egg with any other donor DNA, including an animal's.

Part Animal, Part Human

Joseph Fletcher, a eugenicist in the 1970's dreamed of: "para-humans", or "chimeras".  These part-human, part-animal creatures could be created to perform demeaning tasks or dangerous jobs. Fletcher wrote, "As it is now, low grade work is shoved off on moronic or retarded individuals, the victims of uncontrolled reproduction.  Should we not program such workers thoughtfully instead of accidentally, by means of hybridization?"

Eugenics

Even those who advocate human cloning do not attempt to hide the fact that they would like to simply eliminate all "defective" embryos before they have a chance to develop.  Some health insurance providers advocate "screening" for possible health risks based on the prospective client's DNA and medical history.  Gene therapy attempts to treat genetic disorders by replacing flawed or absent genes with healthy ones.  The failure rate is astronomically high.  No problem for the morally deprived: By using genetic screening, an imperfect child once implanted inside the womb would simply be aborted.  

Same Sex Parents Producing a Child  

Two women involved in a same sex relationship wish to have a child together. Cloning provides it.  One woman donates an unfertilized egg and has the nucleus removed; the second donates the DNA and has it fused with the egg. It is then electrically stimulated and the embryo is implanted in the womb of either woman.

Is Human Cloning Legal?  

That depends on whether one considers an embryo to be human.  Scientists who want to clone try to state that a fertilized egg is not an embryo until at least 14 days. That gives them the opportunity to develop this tiny life and then remove their stem cells for cloning.  Congress overwhelmingly voted last year to ban both therapeutic and reproductive cloning.  There are multiple bills pending in the Senate. The first two are dubbed  “Clone and Kill, whereby the cloned embryo could not be implanted into a woman’s womb and allowed to be brought to full term. However, cloning embryos for research would be allowed.   Enforcing such a bill would be impossible.  Who is going to force a woman to abort a cloned embryo once it is implanted?  The second bill Brwonback’s S1899 would ban ALL cloning.

In Summary

The selfish and cannibalistic act of destroying one human life to create or benefit another should speak clearly enough for itself. But let's look at another aspect. How does one clone the warmth of human love, the empathy felt for one another, or deep human desires to nurture relationships?  These are all parts of the individual you will not find in DNA; the very soul that cannot and should not be artificially duplicated.   What happens to the mind of a child who is cloned after another and no longer has something totally special of his own to offer?  People are loved for who they are on the inside, not for who they appear to be on the outside.  How can such a child ever be assured that he is loved for who he is and not for the person from whom he was cloned?  In creating these persons, we have robbed them of the most basic freedom afforded to mankind - the right to exist as an individual.

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